Source: comicsbeat.com
9. Black Panther
Woooo! Man, everybody loves Black Panther right now, probably because that movie was pretty darn good. But he appeared in other media first!
Specifically, T'Challa made it to the screen in 1994’s Fantastic Four animated series, which was appropriate, because he did make his first appearance in an issue of the FF comic book. This episode is a loose adaptation of that issue. In it, Panther summons the Fantastic Four to Wakanda to help defeat Ulysses Klaw, the dude with a sonar dish for a hand who dresses like a circus tent exploded on him. In this episode, the Panther is portrayed by"¦Keith David!! You know, the awesome actor and voice actor whose voice you'd immediately recognize? Yeah, that's him!
But the first Black Panther-starring thing was"¦Well, it depends. In theory, you could count Ultimate Avengers 2: Rise of the Panther because his name is in the title, but it would probably be the 2010 animated series based on the Marvel Knights series.
That one's pretty good!

