Source: boundingintocomics.com

Chapter Seven: Drax the Destroyer Defeats Thanos

Annihilation time, folks!!!

When Annihilus decided to conquer everything that ever was, Thanos thought that seemed like a pretty sweet deal and hopped on board as an ally. This turned out to be the wrong call, though. After Thanos helped Annihilus capture Galactus, Moondragon revealed to the Mad Titan that Annihilus's plans weren't exactly for domination of the galaxy. No, his plans were to annihilate it.

They wanted to burn down the friggin' universe, and contrary to his previous attitude, Thanos was super not down with that. He very much wanted to rule, not to destroy, at least not since his Infinity Gauntlet-induced revelation.

Thanos had a change of heart and went to release Galactus. At that point, he had another change of heart. By which I mean his heart was shifted from inside his body to a different locale when Drax the Destroyer punched through Thanos's chest and ripped it out.

Lesson Thanos Should Have Learned: Look behind you, my dude. Drax isn't exactly sneaky; he shouldn't be able to catch you by surprise.