Source: comicvine.gamespot.com

4. East Coast/West Coast

Runaways #9-12 (2005)

Hey, hey, folks, it's guest star time!

Yeah, there are guest spots in Runaways prior to this point, but this arc is just Vaughan let loose to play with all of the toys he wants. After someone who looks a lot like Cloak puts Dagger in a coma, the real Cloak turns to the only people he has left: the Runaways. But even as all this is happening, the New Avengers are hunting him down.

This arc is pretty solid. Especially the Spider-Man bits. Holy Lord, Vaughan should have been on a Spidey book. Also, Molly’s initial encounter with Wolverine, Captain America, and Iron Man is incredibly funny. Vaughan clearly wanted to pump the guest stars in this arc, and tying it back to Cloak and the original series was a wonderful idea. The Marvel Universe is a super fun playground, and it's always nice to see people take advantage of that.

I love the original New Avengers team; they're super fun, and very well written in the brief snippets we get.