Professor Pyg

This might seem like a strange entry, but Professor Pyg has a shot at winning the Biggest Twisted Villain title. If The Batman is to largely take place in Arkham (as suggested prior to Affleck’s departure), Pyg would fit in perfectly.

Pyg is an insane scientist who is keen on creating the perfect human. To accomplish this, he attaches a mask to a victim’s face, and the mask slowly alters the host’s head. Then Pyg surgically alters the host’s body, and his victims become Dollotrons. Their purpose is to follow their master’s orders.

If the movie takes place in Arkham, and Arkham is under the rule of some secret villain, Batman would find a dangerous opponent in Pyg and his hosts. And we have no doubt that Serkis could bring this weird, insane villain to life.