Blade vs. Morbius

Kevin Feige revealed that Marvel will focus, during the first Spider-Man film, on villains which weren’t seen before on the silver screens. Morbius can be one of those villains – of course, Blade’s backstory will also be rewritten, since in the comics he is bitten by Morbius and thus gains his powers.

But yes – this is the best way for Blade to enter the MCU: as a supporting character for Spider-Man. If it will be so, the vampires will also be introduced, thus opening the door for all the other opportunities mentioned before.

So if there is just the slightest possibility, then this would be it.