Killed by the Punisher

There are numerous What If? stories in which Wolverine dies when he would otherwise have no problem regenerating. The Punisher Kills the Marvel Universe is one of these stories.

In this alternate reality, the loss of Castle's family during a fight between superheroes and aliens is collateral damage. So the Punisher has all of the big superhero groups in his sights. From Avengers, to Fantastic Four, to X-Men, nobody is safe. And, as the title suggests, the Punisher is actually highly successful in this endeavor.

While Wolverine does survive for a longer period of time than others, Castle does eventually kill him – although, to be honest, there’s no way Logan could lose a fight against Punisher under normal circumstances. So, after a long and brutal fight, Wolverine stabs himself with his own claws. Castle then throws him into an electric transformer.

With all of his flesh burned away, there is nothing left to heal. What was once Wolverine is now just a smoking skeleton.