2. Complicated family problems

The continuous failing health of Aunt May, financial crisis is definitely going to run at the back of the head of Spiderman. So, when dealing with villains, if there are personal thoughts and memories running through his mind, it is certainly going to act into the way he defends the people from the onslaught of the villains. This vulnerability is found in most of the superheroes that have remaining family, and particularly affects Spiderman in the worst possible sense.