You can deduct medical expenses, but only the portion exceeding 7.5% of your adjusted gross income. If your AGI is $80,000, that's a $6,000 floor. However, many people forget to include often-overlooked costs like mileage to doctor visits (21 cents per mile in 2024), prescription copays, dental work, vision correction, and even certain home modifications for medical reasons. Keep meticulous records throughout the year—that accumulated total might finally push you over the threshold and into deduction territory.