Silk

It’s all genetics here. Basically, Silk is the only one with whom Spider-Man can actually be, simply because they both got their powers in the same way, from the same spider. And if the rumors are true and we get a Spider-Man universe, then Silk will be in it.

So I do hope that Silk is featured and that her primal connection to Peter Parker will be featured. However, I doubt that this will happen during Homecoming. Instead, I believe it will happen much later on, when the MCU will have already passed the Infinity War threshold.

Aren’t you interested in seeing such a relationship, too? These two complement each other and, basically, they are made from the same clay. What could go wrong?